Another strong year for Shire

DividendMax Ltd.

Another strong year for Shire

Another strong year for Shire with revenues exceeding $4 billion for the first
time and Non GAAP EPS up 26% to $5.34.

Good 2012 earnings growth expected.

February 9, 2012 - Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty
biopharmaceutical company, announces results for the year to December 31, 2011.

Financial Highlights Full Year 2011(1)

Product sales $3,950 million +26%

Total revenues $4,263 million +23%

Non GAAP operating income $1,357 million +27%

US GAAP operating income $1,109 million +40%

Non GAAP diluted earnings per ADS $5.34 +26%

US GAAP diluted earnings per ADS $4.53 +43%

Non GAAP cash generation $1,391 million +3%

Non GAAP free cash flow $879 million +11%

US GAAP net cash provided by operating activities $1,074 million +12%

Companies mentioned